Patents


Reich, S.; Pino, M.;  Trippe, AJ.;  Ngyuen, D., HIV Protease Inhibitors and Methods of Making the Same, US5714518

HIV protease inhibitors, obtainable by chemical synthesis, block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and possibly other anti-vital agents as ingredients, are thus suitable for the treatment of the HIV virus known to cause AIDS.


Anthony J. Trippe, Karen A. Lucas, Mark E. Piekenbrock, Mark A. Roys, Puduhai N. Sreeram, William F. Bartelt, Alan H. Lipkus, Roger J. Schenck, John L. Macko, William Fisanick, Method and system for substance relationship visualization, US20070211059

A method, system, and software of relating metadata to chemical structures includes displaying chemical structures in a first display area and displaying metadata related to the chemical structures in a second display area. In response to a change in the display of one of the chemical structures in the first display area or the metadata in the second display area, automatically dynamically changing the display in the other of the first display area or the second display area to display changed data based on its relation to the changed data in the one of the first display area or the second display area.


Anthony J. Trippe, Jeffrey V. Fisher, William F. Bartelt, Roger James Schenck, Kirk Crandall Schwall, Jay P. Vondran, Todd A. Hill, James A. Vorbau, Stephen D. Powers, Method and system for displaying relationship between structured data and unstructured data, US20070244859

A method, system, and software of relating structured data to unstructured data includes displaying unstructured data in a first display area and displaying structured data related to the unstructured data in a second display area. In response to a change in the display of one of the unstructured data in the first display area or the structured data in the second display area, automatically dynamically changing the display in the other of the first display area or the second display area to display changed data based on its relation to the changed data in the one of the first display area or the second display area.


Anthony J. Trippe, Karen A. Lucas, Jeffrey M. Wilson, Method and system for preclassification and clustering of chemical substances, US20070213965

Systems and methods for intuitive visualization of the relationships between molecules. Acyclic and cyclic compounds are converted to base frameworks. The molecules are mapped with each base framework, representing a multitude of molecules, mapped as a single point. The base frameworks are positioned relative to each other using similarity tests as applied to metadata which are associated with the atoms and bonds frameworks of the molecules.